Why the Body Craves Balance and How (PEA)+ Offers Support*

Why the Body Craves Balance and How (PEA)+ Offers Support*

Some people are creatures of habit, feeling lost without their planner and scheduling their days down to the hour and minute. Others of us thrive without a plan or schedule in place, with no two days ever looking quite the same. No matter which camp you consider yourself to be in, your body loves consistency and routine – craving balance as its happy place.

Officially this is called homeostasis, and it’s your body’s very own “zone of excellence,” where it possesses the energy, time and resources to be its very best self. But life happens, and things both within and outside your control can impact that delicate balance. Thankfully, there are natural ways to maintain homeostasis and keep you in balance no matter what life throws your way.

In this blog we’ll cover how the Enzyme Science formula (PEA)+ offers support for physiological stress or discomfort associated with occasional stiffness and compromised tissue function as a result of overexertion and everyday stress.* Read on to learn more about your body’s ideal balance, along with the two key ingredients in (PEA)+ from Enzyme Science, palmitoylethanolamide and Meriva® curcumin.

What is Physiological Stress?

Physiological stress is a perfectly normal response in life, but it doesn’t always come at predictable times or convenient ones.* (As much as we all wish we could schedule such events, that’s simply not an option!) Physiological stress is an important way that the brain alerts us that we should shift our attention to a certain area of the body.* According to a 2012 National Health Interview Survey, more than five in 10 of all adults in the United States reported they had experienced some level of physiological stress or discomfort in the prior three months.1

Plenty of culprits exist: Aging, inactivity, everyday stress, lifestyle and overexertion can all lead to occasional discomfort.*

What Does (PEA)+ Do to Support the Body?*

This formula from Enzyme Science relieves physiological stress and soreness or discomfort associated with occasional pain, stiffness and compromised tissue function as a result of overexertion and everyday stress.*

When we live in a state of optimal health, the body naturally produces an amount of PEA (palmitoylethanolamide) that maintains homeostasis. However, negative stimuli (and our modern lives) can sometimes compromise this balance. In turn, the body’s response can cause lead to a deficiency in PEA production. Supplementing with PEA works with the body’s natural processes to support this delicate balance, calm discomfort and promote PEA levels needed to maintain overall well being.* In combination with Meriva® Curcumin, this formula provides natural support for the entire body with a focus on the body's nervous, immune and muscular systems.*

When excited nerves issue sensory information to the brain, the body can react in the form of uncomfortable sensations. In the presence of this discomfort, many commonly choose to deal on their own.1 These consumers turn to easily accessible over-the-counter options such as NSAIDs to avoid the short term discomfort.

One study led by the Director of the Slone Epidemiology Center at Boston University evaluated consumer compliance with recommended NSAID usage. The researchers found that nearly one in five individuals exceeded daily maximum doses during a one-week period. When misused or overused, these OTCs can cause gastrointestinal toxicity, stomach bleeding and kidney or liver damage.

For those experiencing only occasional discomforts, a natural approach may be a better option to  alleviate physical suffering.* Dietary supplements work with the body's natural processes for physiological stress and soreness without the side effects associated with the overuse of OTC options.*

What is PEA?

Palmitoylethanolamide (PEA) is an extensively researched natural ingredient for important neuroprotective actions.*2 This ingredient has been widely used for decades, and it is available in dietary supplements worldwide as an option for the onset of physiological stress.*

What is PEA? PEA is an endogenous fatty acid amide that belongs to the family of biologically active lipids that are increased by the body to soothe discomfort naturally.* Identified over 60 years ago when it was isolated from extracts of brain, liver and muscle of rat and guinea pig, PEA was later found in chicken egg yolk, olive oil, safflower and soy lecithin, peanut meal, and several other foods.

The biological properties and mechanisms of PEA naturally produced by the body involve a variety of effects including those upon glial and mast cells, cannabinoid-2 receptors, NF-kB, and effects on the nuclear receptor peroxisome proliferator-activated receptors (PPARs). Cannabinoid-2 receptors are more often found on immune cells, in the gastrointestinal tract and in the peripheral nervous system. Glial and mast cells naturally play a key role in the body's management of discomfort. PEA enhances the effects of the fatty acid anandamide (also referred to as the "bliss molecule") when it binds to cannabinoid receptors.*

Where can I get PEA?

There are two sources of PEA commercially available. Synthetic forms require the use of powerful synthetic solvents such as toluene. On the other hand, PEA can be naturally derived from safflower lecithin.

Enzyme Science offers (PEA)+, which is a unique blend of PEA from safflower seeds, paired with the well-researched, patented and highly bioavailable curcumin, Meriva® Phytosome.

Curcumin for physiological stress*

If you have every eaten curry or sipped a golden milk latte, you have consumed curcumin. Curcumin is the yellow pigment of turmeric (Curcuma longa L.), the most widely used spice of the Indian cuisine and a major ingredient of curry powders. Curcumin is one of the best investigated ingredients in the supplement industry but shows very poor oral absorption.

Meriva® Phytosome is a patented formulation of curcumin made with sunflower derived phosphatidylcholine. Phytosome® technology improves the bioavailability by offering a higher stability and oral absorption in comparison with unformulated curcumin. Meriva was independently endorsed by the prestigious Cleveland Clinic as the curcumin formulation of choice.

How to Take Enzyme Science (PEA+)

Taking our (PEA+) formula is simple: Take 2 capsules twice daily, with or without food. Consult with a physician prior to use if you are pregnant or nursing, taking medications or have a medical condition.

What’s Inside (PEA)+ from Enzyme Science?

Every 2-capsule serving size of (PEA)+ contains 500 mg Meriva® Curcumin Phytosome Phosphatidylcholine Complex made from Curcuma longa rhizome with 18  to 22% curcuminoids. It also contains 300 mg palmitoylethanolamide (PEA). The 100% vegetarian capsules contain cellulose, water and rice concentrate.

(PEA)+ contains no gluten, milk, casein, soy, egg, artificial colors or flavors – that is the Enzyme Science promise to you.

Enzyme Science formulas are available through the most trusted health-care professionals, as well as at EnzyScience.com. Here’s where to buy (PEA)+.

Other Products You Might Like

MYOMEND™: An advanced proteolytic enzyme blend to support physical recovery.*

  • Vegetarian proteolytic enzymes for muscle & joint function*
  • Includes Rutin to optimize mobility*

About Enzyme Science

At Enzyme Science, we make exceptional formulas for natural digestive health and wellness. From a foundation of unparalleled standards of quality, we source the finest ingredients and validate them with exceptional science. We are the practitioner division of Enzymedica™, the #1 selling enzyme brand in the United States.

The health professionals like yourself, who trust us to help bring exceptional care and superior quality supplements to their practices, are trusted partners. That’s why we remain so committed to excellence. Here’s how we do it.

Our team is committed to producing superior formulas with cutting-edge science to support total health and well-being. We maintain exceptional quality standards. We value clinical research, sustainable and non-GMO sourced materials, and adhere to unsurpassed quality standards that consistently exceed those stipulated by the FDA’s cGMP regulations.

Our vision is to combine Eastern and Western medicine by supporting practitioners who are working toward alleviating their patient's symptoms – and providing support for underlying conditions. We believe that great health can be made possible and easy for everyone, so our goal is to provide just that. Our commitment to excellence is our promise to practitioners who trust us: We deliver exceptional quality and purity, Thera-Blend™ technology and bioavailable sourcing, superior results and patient satisfaction. We never use artificial fillers in our 100% vegetarian formulas, which are also vegan and kosher when possible.

The Enzymedica team established Enzyme Science back in 2011 as an exclusive brand for health-care practitioners. Since then, we have partnered with thousands of health professionals and listened to them to understand how we can better assist them. We strive to help them provide quality care and bring additional value into their practices.

We continue to expand our research and connect with more professionals. In 2021, we assembled some of the world’s most respected health experts for our Scientific Advisory Board. This independent group helps us with education, research and product development. When we set out to create our Scientific Advisory Board, we knew we needed to find experts who were not only leaders in their field and at the forefront of natural health research, but they also needed to share our values. We’re honored that these four individuals have joined our board. They are Dr. Mark Tager, MD, integrative medicine & education expert; Dr. Suzanne Gilberg-Lenz, MD, board-certified OB-GYN/CMO; Dr. Marvin Singh, MD, a world-leading expert in gastroenterology; and Sherry Torkos, B.Sc. Phm., R.Ph., a renowned integrative pharmacist.

We are dedicated to supporting their commitment to health and wellness. It is critical for our business that you succeed in yours, and we’re proud to be your trusted partner.


1 Sansgiry 55, Bhansali AH, Bapat 55, Xu Q. lntegr Pharm Res Pract. 2016 Dec 19;6:1-6. doi:10.2147/IPRP.Sl 03494. eCollection 2017. Review.

2 Scuderi C, Bronzuoli MR, Facchinetti R, et al. Transl Psychiatry. 2018 Jan 31;8(1):32. doi: 10.1038/s41398-017-0076-4.